With the increasing support of MFA using security keys to authenticate in services like GitHub, M365, Google, AWS, Salesforce, and many others, coupled with the prevalent use of VMware desktop virtualization for development and testing, it is more and more of a need to get YubiKeys to passthrough to a Guest VM. This process does NOT require disabling OTP+U2F, as some have suggested. I've tested this thoroughly on VMware Workstation 17 (Windows/Linux) and VMware Fusion 13 (Mac).